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DeCS
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Descriptor English:
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Bone Remodeling
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Descriptor Spanish:
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Remodelación Ósea
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Descriptor Portuguese:
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Remodelação Óssea
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Synonyms English:
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Bone Turnover
Bone Turnovers
Remodeling, Bone
Turnover, Bone
Turnovers, Bone
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Tree Number:
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G11.427.213
G16.762.150
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Definition English:
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The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS. |
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Indexing Annotation English:
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note category: an aspect of bone physiol
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History Note English:
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92
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Allowable Qualifiers English:
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Record Number:
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30227
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Unique Identifier:
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D016723
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Occurrence in VHL:
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Similar:
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DeCS
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